Thursday, September 20, 2007

Complications & Prognosis of Disk Prolapse

Complications and Prognosis of Disk Prolapse

Complications:
Can lead to pain on coughing, laughing, sneezing, urinating, or straining while defecating.
Intense pain radiating down leg (sciatica) due to disk compressing on spinal nerve
Can lead to pain on defecating or urinating if nerves to bowel and bladder are compressed.
Also weakness of the muscles of the genitourinary area. May lead to trouble urinating or erectile dysfunction.
Loss of sensation to buttocks, medial and posterior thigh.

Prognosis:
90% of patients usually fully recover within a month or two with only use of paracetamol or NSAIDs to manage pain
Modified activity to rest the site and physiotherapy will improve the chances of the disk healing back to its pre-prolapse state.
About 10% of patients will require surgery and the success rate depends on the extent of the damage.
Day procedure with two to four week recovery time.
Usually works but general risks of surgery apply.

Surgical Mx of Back Pain

Surgery is not always the best option for treatment of sciatica or back pain, as it can cause complications in some cases. Surgery is advised only for a selective group of people with back pain. The pain must present for at least four weeks, and must be so severe that it affects normal function. These are some of the types of surgeries that are performed for back pain and sciatica:

Laminectomy, the removal of the entire lamina or Laminotomy, removal of part of the lamina is a treatment method for back pain resulting from spinal stenosis, or spinal tumours. Part of the lamina is cut away to uncover the ligamentum flavum, which is then incised to enter the spinal canal. The cause of the compression (eg a herniated disk) can then be corrected.

Discectomy Is the treatment of a herniated disk (where the gel-like substance in the intervertebral disk breaks through the exterior). This is usually done with laminectomy. In a discectomy the gel substance which has broken through and is compressing the spinal nerve is removed. This returns the disk to its normal shape, and relieves the pressure on the spinal nerve.

Rhizotomy is a procedure whereby the sensory nerve roots are first separated from the motor ones and then cut. Identification of the nerve fibres to be cut is then made by means of electrical stimulation. The one(s) producing the pain or other problems are identified in this way, and then selectively cut.

Foraminotomy is the treatment for pinched nerves. The opening where the spinal nerve exits the spine (foramen or neuroforamen) is surgically enlarged. This relieves compression of spinal nerve.

Spinal fusion is when vertebrae are fused together because abnormal positioning of the vertebrae is putting pressure on the nerve. A bone graft may be used, or devices such as cages, plates, screws and rods, to fuse the vertebrae.

Most spinal surgeries are not an emergency, so it is possible to prepare for surgery. It is important to eat a balanced diet with adequate vitamin supply, to help wound healing and reduce risk of infection. Exercise (which is approved by doctor) can increase cardiovascular endurance and speed up recovery. More body weight strains the spine, slows healing process, and increases post operative pain. So losing some weight (if required) before surgery may be beneficial. Also, smokers are encouraged to quit, as it can increase the chance of complications.

Sciatica and neoplasias of the spine

Like other forms of sciatica pain is caused when a neoplasia compresses the spinal roots. Patients present with typical symptoms of sciatica but may also have other symptoms including slight paralysis, spinal deformity (e.g. scoliosis, kyphosis), and fever. Sciatic pain can occur at rest, be worse at night, and may or may not be related to activity. Neoplasias need to be ruled out if sciatic pain does not resolve or if neurologic deficit is experienced (one of Murtagh’s ‘unmissables’).

There are three kinds of neoplasia that can affect the spin:
• Extradural (similar to epidural only does not have to be immediately outside the dura mater.
• Extramedullary (outside of any medulla oblongata)
• Intramedullary (within the bone or medullar oblongata)

Both extradural and extramedullary neoplasias can cause compression of the spinal cord. This generally takes weeks to months and typically present with root pain and sensory loss. Intramedullary tumours are rarer and typically progress over many years.

Neoplasias of the spine are typically secondary cancers formed by metastatic neoplasias of the bronchus, breast, prostate, lymphoid, thyroid or skin (melanomas), and so may often imply more serious implications.

Wednesday, September 19, 2007

Facet Joint Injections

Facet joints provide stability and give the spine the ability to bend and twist.
Facet joints are made up of the two surfaces of adjacent vertebrae, which are separated by a thin layer of cartilage. The joint is surrounded by a capsule containing synovial fluid.

Facet joints can become painful due to arthritis of the spine, a back injury, or mechanical stress of the back.
An injection of a steroid medication is given into the facet joint, which anaesthetises the joint and blocks the pain.

There are two reasons for having facet joint injections:
1) For diagnosis
2) For pain relief

To determine if the facet joint is the cause of the pain, a small amount of anaesthetic is injected into the facet joint. If this reduces or moves pain, it indicates that the facet joint is the source of the pain.

Once it’s known that the facet joint is the source of the pain, therapeutic injections (anaesthetic and anti-inflammatory, usually time-release cortisone) may give relief for longer periods of time. The pain relief from a facet joint injection is intended to help the patient better tolerate other forms of treatment (such as physiotherapy) to rehabilitate their back injury.

Extra info:
Where pain is felt due to facet joint problems depends on which facet joints are affected:
Cervical facet joints: pain felt in the head, neck, shoulder and/or arm
Thoracic facet joints: pain felt in upper back, chest and/or arm (rarely)
Lumbar facet joints: pain felt in lower back, hip, buttock and/or leg

Thursday, September 13, 2007

Treatment of Osteoarhtirits-Surgery

Several surgical options:

Total Hip replacement or arthroplasty
Arthroscopic levage or debridement
Using a small camera (arthroscope)Lavage-using saline to flush out blood, fluid or loose debris inside your joint- or Debridement-which removes loose fragments of bone or cartilage inside your joint- are performed. These procedures may provide short-term pain relief and improved joint function for some people, not really for severe osteoarthritis
Repositioning bones or osteotomy
Surgeons can also reposition your bones to help correct deformities
Fusing bones or arthrodesis
Surgeons also can permanently fuse bones in a joint to increase stability and reduce pain. The fused joint, can then bear weight without pain, but has no flexibility.

Total Hip Replacement At A Glance
• The prosthesis for a total hip replacement can be inserted into the femur bone with or without cement.
• Chronic pain and impairment of daily function of patients with severe hip arthritis are reasons for considering treatment with total hip replacement. Age important (usually for 60+ yo patients).
• Complication and risks of total hip replacement surgery have been identified.
• Preoperative banking of the blood of patients planning total hip replacement is considered when possible.
• Physical therapy is an essential part of rehabilitation after a total hip replacement.
• Patients with artificial joints are recommended to take antibiotics before, during, and after any elective invasive procedures (including dental work).


What is a total hip replacement?
• the diseased cartilage and bone i.e. the diseased acetabulum and femur, are replaced with a metal ball and stem (“prosthesis”) inserted into the femur bone, and an artificial plastic cup socket.
• prosthesis inserted into the central core of the femur, then fixed with a bony cement called methylmethacrylate. Alternatively, a "cementless" prosthesis is used which has microscopic pores that allow bony in growth from the normal femur into the prosthesis stem. "cementless" hip is felt to have a longer duration esp. good for younger patients

Who is a candidate for total hip replacement?
• performed most commonly b/c of progressively severe arthritis( esp. O/A) in the hip joint
• Other conditions leading to total hip replacement include bony fractures, rheumatoid arthritis, aseptic necrosis-caused by fracture, drugs-alcohol, prednisone, prednisolone, diseases-systemic lupus erythematosus
• The progressively intense chronic pain together with impairment of daily function like walking, climbing stairs and rising from a sitting position, eventually become reasons to consider a total hip replacement.
• Because replaced hip joints can fail with time, whether and when to perform total hip replacement are not easy decisions, especially in younger patients. Replacement is generally considered after pain becomes so severe that it impedes normal function despite use of antiinflammatory and/or pain medications
• 60s are good age. Surgeons unlikely to undertake operation earlier (i.e at 55 yo) b/c of 20% chance that prosthesis will fail within 10-12yrs
• A total hip joint replacement is an elective procedure, a decision made with an understanding of the potential risks and benefits.

What are the risks of total hip replacement?
• The risks of total hip replacement include blood clots in the lower extremities (pulmonary embolism), difficulty with urination, local skin or joint infection, fracture of the bone during and after surgery, scarring and limitation of motion of the hip, and loosening of the prosthesis which eventually leads to prosthesis failure.
• Because total hip joint replacement requires anesthesia, the usual risks of anesthesia apply and include heart arrhythmias, liver toxicity, and pneumonia.
What does the preoperative evaluation entail?
• Total hip joint replacement can involve blood loss, so patients planning to undergo Rx often will donate their own (autologous) blood to be banked for transfusion during the surgery.
• The preoperative evaluation: a review of all medications being taken by the patient, complete blood counts, electrolytes (potassium, sodium, chloride, bicarbonate), blood tests for kidney and liver functions, urinalysis, chest x-ray, EKG, and a physical examination.
• Any indications of infection, severe heart or lung disease, or active metabolic disturbances such as uncontrolled diabetes, may postpone or defer total hip joint surgery.

What will it be like for the patient after surgery?
• A total hip joint replacement takes two to four hours of surgical time
• After surgery, taken to a recovery room for immediate observation-one to four hours. The lower extremities closely observed for both sensation and circulation.
• Upon stabilization, the patient is transferred to a hospital room.
• During the immediate recovery period, patients are given intravenous fluids, to maintain a patient's electrolytes as well as for administering antibiotics.
• Pain control medications are commonly given through a patient-controlled analgesia (PCA) pump whereby patients can actually administer their own dose of medications on demand. Pain medications occasionally can cause nausea and vomiting. Anti-nausea medications may then be given.
• Immediately after surgery, patients are encouraged to frequently perform deep breathing and coughing in order to avoid lung congestion and the collapse of tiny airways in the lungs.

What is involved in the rehabilitation process after total hip joint replacement?
• After total hip joint replacement surgery, patients often start physical therapy immediately! Eventually, rehabilitation incorporates stepping, walking, and climbing. Initially, supportive devices such as walker or crutches are used.
• Physical therapy is extremely important in the overall outcome of any joint replacement surgery. The goals of physical therapy are:
o to prevent contractures-resulting from scarring of tissues around joint, loss ROM
o improve patient education
o strengthen muscles around the hip joint through controlled exercises.
o given home exercise programs to strengthen muscles around the buttock and thigh.
• Most patients attend outpatient physical therapy for a period of time while incorporating home exercises regularly into their daily living.

Full Blood Examination (FBE)

A complete blood count will normally include:
Red cells:
• Total red blood cells - The number of red cells is given as an absolute number per litre.
• Haemoglobin - The amount of hemoglobin in the blood, expressed in grams per litre. (Low hemoglobin is called anemia.)
• Haematocrit or packed cell volume (PCV) - This is the fraction of whole blood volume that consists of red blood cells.
• Mean corpuscular volume (MCV) - the average volume of the red cells. Anemia is classified as microcytic or macrocytic based on whether this value is above or below the expected normal range. Other conditions that can affect MCV include thalassemia and reticulocytosis.
• Mean corpuscular hemoglobin (MCH) - the average amount of hemoglobin per red blood cell.
• Mean corpuscular hemoglobin concentration (MCHC) - the average concentration of hemoglobin in the cells.
• Red blood cell distribution width (RDW) - a measure of the variation of the RBC population

White cells:
• Total white blood cells - All the white cell types are given as a percentage and as an absolute number per litre.
• Neutrophils - May indicate bacterial infection. May also be raised in acute viral infections.
• Lymphocytes - Higher with some viral infections such as glandular fever and. Also raised in lymphocytic leukaemia CLL.
• Monocytes - May be raised in bacterial infection
• Eosinophils - Increased in parasitic infections.
• Basophils

Platelets:
Platelet numbers are given, as well as information about their size and the range of sizes in the blood.

Other Tests:
• CRP
~ C Reactive Protein
~ plasma protein produced by the liver as part of the inflammatory process
~ test used as an indicator of inflammation
~ increased CRP levels = inflammation
~ often indicative of rheumatoid arthritis
• ESR
~ Erythrocyte Sedimentation Rate
~ measures how long it takes for blood to separate into red cells and plasma
~ an increased ESR is indicative of inflammation
• Serology
~ looking at antigen and anti-bodies

Joints affected by osteoarthritis compared to rheumatoid arthritis and their signs and symptoms

Osteoarthritis
OA is the most common type of arthritis. It affects the cartilage in the joints. Cartilage cushions the ends of the bones involved in a joint, and in OA the cartilage breaks down. With the ends of the bones unprotected, the joint doesn’t function in its normal smooth way.
OA most commonly occurs in the fingers and weight bearing joints, mainly knees, feet, hips and back.

Signs and Symptoms
Symptoms of OA vary. Most individuals remain essentially free of symptoms. Symptoms may include any of the following:
• Pain and stiffness in the joint
• Swelling
• Joint instability
• Loss of function
• Joint tenderness
• Crepitus on movement
• Limitation of range of movement
• Joint instability
• Joint effusion and variable levels of inflammation
• Bony swelling
• Wasting of muscles


Rheumatoid arthritis
In RA, inflammation (pain, heat and swelling) affects joints, and sometimes other organs of the body. RA is an auto-immune disease, where the immune system attacks the synovial membrane lining the joints, and inflammation occurs. Treatment is vital to minimise damage to cartilage and bone within the joint. RA can start in any joint, but often starts in the smaller joints of the fingers, hands and wrists. Most commonly affected joints are in the hands, feet, shoulders and knees.

Signs and Symptoms
Symptoms vary from person to person and may include:
• Tender, warm, swollen joints
• Persistent fatigue and feeling "run down"
• Joint stiffness more noticeable in the morning
• Limitation of movement
• Muscle wasting
• Deformities develop as the disease progressed
• Generally, both sides of the body are affected similarly.

http://www.arthritisvic.org.au
http://www.arthritis.org
Kumar and Clark

Wednesday, September 12, 2007

Medical Management for Osteoarthritis


v Treat psychological and/or social factors
v Educate patient about disease
v Reduce pain, distress and disability
v Positive coping mechanisms

Physical measures
v Weight loss
v Exercise for strength and stability
v Hydrotherapy (especially for lower limb)
v Local heat, ice packs, massage, rubifacients local NSAID gels
v Complementary medicine

Medication
v Should only be used in severe disease
v Analgesics
v NSAIDs used intermittently
v Some NSAIDs said to increase cartilage damage, while others are ‘chondroprotective’, though these claims remain unproven
v
Intra-articular corticosteroid injections à short term improvement
v Frequent injections into same joint should be avoided
v Chondrotin sulphate and glycosaminoglycan à efficacy unproven

Tuesday, September 11, 2007

Complementary therapies and osteoarthritis

Complementary therapies in the management of osteoarthritis include draw on a wide field of philosophies including:

Magnetic therapy – mixed levels of success, some people swear by it while others have found that benefits are few and far between. Little evidence of negative effects but those with pacemakers should avoid.


Acupuncture – studies into the benefits of acupuncture have come across many difficulties in accessing the efficacy of the treatment. However, a recent study in patients with osteoarthritis of the knee showed that in addition to the standard treatment (anti inflammatory medications and pain relieving medications) patients showed improved function at 8 weeks and decreased pain at 14 weeks.
(Arthritis Victoria)


Glucosamine –occurs naturally in the body and appears to be involved in the formation and repair of cartilage. There is growing evidence that glucosamine sulphate could prevent changes in joint structure associated with osteoarthritis and also significantly improve symptoms. Some clinical studies of glucosamine indicate that 500mg taken three times daily orally (a total of 1,500mg) may help relieve pain and help preserve cartilage

Glucosamine sulphate is made from lobster shells and so those with shellfish allergies are often sensitive to these supplements. Glucosamine is technically a carbohydrate and while it is not converted into glucose diabetics should be carefully monitored in case of any unexpected interactions. Gastrointestinal upsets, sleepiness, headaches or skin reactions may also occur in some people. Pregnant women should avoid taking glucosamine as not enough research into the long term effects on an unborn child have been completed.


Chondroitin – another dietary supplement used by those suffering from OA. Less research has been done into chondroitin than glucosamine, but like glucosamine it has been shown to be safe (at least short term) and to be a valid option to use in conjunction with other treatments, as it seems to increase mobility and analgesic effects.

People taking blood-thinning medications should consult their doctors as chondroitin may also increase bleeding. It may also cause stomach upsets and may interact with other drugs and supplements.


Things to consider:
- Drug interactions and other factors that may negatively interact with any treatments/patient factors (eg food allergies, pregnancy etc…)
- Complementary therapies may take several weeks before any benefits may be noticed (and so are often best used in conjunction with other treatments)
- While using complimentary therapies patients may find it useful to keep a journal recording treatment, symptoms and activities for a month so that they can access any benefits.
- Many complementary treatments are not as heavily regulated as other treatments and so patients should be particularly weary of products that:
• Claim to “cure” arthritis
• Claim to work for all types of
• Arthritis and / or other disorders
• Claim to be free from all side effects
• Don’t list the ingredients.

Monday, September 3, 2007

Management of Carpal Tunnel Syndrome


· General measures

o Avoid repetitive wrist and hand movements

o Improved wrist positioning


· Splint to hold the wrist in dorsiflexion overnight

o This relieves the symptoms and is diagnostic

o If used nightly for several weeks, it may produce full recovery

o Most effective if used within 3 months of the onset of symptoms


· Corticosteroid injection into the carpal tunnel

o Helps in 70% of cases

o Recurrence may occur (80% after 1 year)

o More effective than oral treatments

o Risk of injecting into median nerve


· Nerve conduction studies followed by surgical decompression of carpal tunnel

o Used when symptoms persist or nerve damage is suspected – ie,
thenar atrophy or motor weakness

o Outpatient procedure

o long palmar curvilinear incision to facilitate division of the
transverse carpal ligament and its overlying structures

o Endoscopic carpal tunnel release is a newer procedure that allows
division of the transverse carpal ligament with the overlying structures left
intact

o Wrist splinted for 3 – 4 weeks after surgery


· Diuretics, NSAIDS, oral corticosteroid, pyridoxine (vit B6)

o Varying degrees of success

o Studies show that NSAIDS and diuretics confer no benefit

o Oral corticosteroid shown to work


References


Kumar, P. and Clark, M. (2005) Clinical Medicine 6th Ed, Elsevier Saunders, Philadelphia

Anthony, J. (2003) Management of Carpal Tunnel Syndrome. American Family Physician, 68 (2), 265-272

Available: http://www.aafp.org/afp/20030715/265.pdf